I lead global clinical operations with a focus on clarity, momentum, and high‑quality execution—helping teams remove bottlenecks, align cross‑functional partners, and keep studies advancing efficiently and inspection‑ready.
Get in TouchLeading complex studies across therapeutic areas with a focus on efficiency, quality, and accelerated timelines.
Ensuring ICH/GCP alignment, proactive risk mitigation, and ongoing inspection readiness.
Driving performance, improving feasibility and site engagement, and removing operational bottlenecks.
Providing structured strategic thinking, communication clarity, and messaging that aligns stakeholders, supports decision‑making, and drives teams toward shared outcomes.
Stepping into high‑complexity environments to connect pieces, fill operational gaps, and create momentum—so teams can deliver more effectively with greater confidence and less friction.
Fractional leadership, interim management, and organizational scaling support.
Optimizing startup timelines and improving site engagement strategies.
Ensuring alignment, performance monitoring, and escalation management.
Hello! My name is Yelena Sigal. With more than 15 years of experience leading global clinical operations, I’ve supported high‑stakes projects across infectious diseases, oncology, and multiple other therapeutic areas. My work centers on solving operational challenges, strengthening participant recruitment and retention, and building patient‑focused strategies that work in fast‑moving, complex environments. I’m deeply committed to learning, innovation, and the research community.
My goal is simple: to help teams progress with fewer obstacles, stronger structure, and operational excellence at every step.
I provide both strategic and hands‑on clinical operations support to high performing teams—accelerating timelines, raising operational quality, and ensuring strong vendor and CRO performance. I bring clarity, structure, and momentum to trial execution through services such as:
I collaborate closely with cross‑functional teams, offering practical solutions and the kind of partnership that makes complex work feel lighter and more manageable.
Whether you need strategic guidance, operational leadership, or project-level support, I'm here to help.
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